Our DNA is often pictured as a simple spiral, like a piece of rope held taut. But inside cells, it folds into a complex three ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how ...

A UK research team analyzed the three-dimensional structure of DNA in rare immune cells called ILC3 to identify genes ...

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated-able to read not only the ...

The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, tiny loops called microcompartments remain (and even strengthen) while ...

Cancer isn't just about broken genes—it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off neighborhoods from essential services. That's what happens inside cells ...

Learning how nerve cells repair themselves could lead to new treatments for nerve injuries Palmisano carried out the work while at Imperial College London with co-investigator Professor Simone Di ...

Congenital heart disease is the most common birth defect, affecting approximately 1 in 100 babies born each year. One of the many causes of this disorder is having only one functional copy of the gene ...