Point mutations change one or very few nucleotides in DNA, but they cause an estimated 30,000 genetic diseases in humans. For example, children born with Progeria age rapidly and die before adulthood, ...
Scientists and physicians can better assess precision genome editing technology using a new method made public today by St. Jude Children's Research Hospital. Significant amounts of time and resources ...
At least five groups have independently invented a new class of CRISPR gene editing tools called dual base editors. The systems combine the functions and components of two CRISPR base editors, which ...
A reasonable idea, suggests Sekar Kathiresan, MD, co-founder and CEO of Verve Therapeutics, is the development of a one-time treatment—a single spelling change in the DNA of a liver gene in an adult ...
Scientists at St. Jude Children’s Research Hospital report that they have developed an unbiased, sensitive, and resource-efficient method to identify small, off-target sites that pose a safety risk ...
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