"By cleverly combining new techniques for analyzing DNA at the level of individual molecules, we can achieve real breakthroughs in research into conditions such as dementia," predicts Professor John ...

The first DNA sequencing was performed by Sanger and co-workers in the 1970s, using a method based on the attenuation of the growing nucleotide chain with dideoxythymidine triphosphate (ddTTP). The ...

DNA methylation is a highly studied epigenetic modification that regulates genome function and plays key roles in development and disease 1. It is linked to a broad range of conditions, including ...

Researchers from the Faculty of Engineering at The University of Hong Kong (HKU) have developed two innovative deep-learning algorithms, ClairS-TO and Clair3-RNA, that significantly advance genetic ...

A whole-genome sequencing approach shows early promise over current commercial methods for identifying more patients likely to benefit from PARP inhibitor cancer treatments, according to a study led ...

Antibiotic resistance is often framed as a hospital problem, but a growing body of evidence shows that the environment plays ...

PacBio has announced plans to enhance its methylation detection capabilities in HiFi sequencing by licensing advanced methods from Professor Dennis Lo and his team at The Chinese University of Hong ...