For more than a century, Mendelian genetics has shaped how we think about inheritance: one gene, one trait. It is a model that still echoes through textbooks—and one that is increasingly reaching its ...

Retinitis pigmentosa (RP) is an eye condition that can be genetic. In this way, people usually need to inherit two copies of a genetic variation that causes RP, one coming from each parent. RP may ...

Hemophilia is a bleeding disorder that can affect the blood’s ability to clot properly. In most cases, people inherit the gene variations for hemophilia in an X-linked recessive inheritance pattern.

Hypermobile Ehlers–Danlos syndrome (hEDS) is one of the most common heritable connective tissue disorders. Early estimates have reported that this genetic disorder affects at least one in 5,000 ...

Rare genetic traits are features that are uncommon within the general population. They can lead to different observable features or to rare physical abilities. Rare genetic traits are typically ...

Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...

Obesity is a complex disorder that is dependent on environmental and genetic factors. Severe obesity, which is otherwise known as class III obesity, is a chronic condition that increases the risk of ...

The same pathogen can often elicit very different responses from different people. Scientists sought to understand more about ...