For many people with major depressive disorder (MDD), the first or second antidepressant doesn't cut it. Maybe your sleep gets better. Maybe the darkest thoughts ease up. But you still slog through ...
Although antidepressants are a mainstay of MDD treatment, they are plagued by poor efficacy, high rates of relapse, and intolerable side effects. 40,41 Second-generation antidepressants, including ...