Innate immunity is a foundational field in immunology, critical for understanding how organisms sense and respond to danger, be it pathogens or sterile ...
When thinking about the immune system, most people think about B and T cells and how they can be trained to recognize pathogens, preventing re-infections. Besides this "adaptive" immune system, we ...
The BCG vaccine protects against tuberculosis, but by inducing trained immunity it also protects against many more respiratory infections. International research led by Radboud University Medical ...
Vaccines provide a front-line defense against dangerous viruses, training adaptive immune cells to identify and fight specific pathogens. But innate immune cells — the first responders to any bodily ...
Research from Radboud university medical center reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells. Previously, it was believed that the memory of ...
From Left to Right: Iñaki Robles-Vera, David Sancho, Vanesa Núñez, Manuel Rodrigo-Tapias, Sarai Martínez-Cano, Marcos Femenía-Muiña, Ana Redondo-Urzainqui, Aitor Jarit-Cabanillas, Manuel J. Gomez, Ana ...
Clinical research has long focused on ways to harness the actions of the immune system. From vaccines to immunotherapies, ...
A study led by David Sancho at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid reveals how an increase in intestinal permeability allows the natural gut bacteria to cross the ...
Researchers have shown that innate immune training, also known as trained immunity (TRIM), leads to aggravated bone loss in experimental models of periodontitis and inflammatory arthritis. Clinical ...
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