Artificial intelligence has solved one of biology’s most stubborn mysteries: how proteins fold into their intricate three-dimensional shapes. But as the field shifts from prediction to application, a ...

Gero, a biotechnology company developing novel therapeutics for aging and chronic diseases, has released ProtoBind-Diff, a novel masked diffusion language model that generates drug-like molecules for ...

Over the past six years, artificial intelligence has been significantly influenced by 12 foundational research papers. One ...

AI protein function prediction uses machine learning models trained on sequence and structural data to infer protein roles at ...

They build our bodies and orchestrate the molecular processes in cells that keep them healthy. They also present a wealth of targets for new medications. From everyday pain relievers to sophisticated ...

Within the past few years, models that can predict the structure or function of proteins have been widely used for a variety of biological applications, such as identifying drug targets and designing ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

New computer simulations that model every atom of a protein as it folds into its final three-dimensional form support the existence of a recently identified type of protein misfolding. Proteins must ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

Fruit flies, mice, zebrafish, yeast and the tiny worm C. elegans are model organisms that have carried modern biology on ...