Statistically significant does not mean clinically significant. In the latest Stats, Stat! animated video from 𝘕𝘌𝘑𝘔 𝘌𝘷𝘪𝘥𝘦𝘯𝘤𝘦, Nigam and colleagues explain the minimal clinically important difference. | The New England Journal of Medicine

Is acetaminophen safe to use during pregnancy? NEJM Clinician Editor-in-Chief Raja-Elie Abdulnour, MD, explains a systematic review that examined associations between prenatal acetaminophen exposure and validated neurodevelopmental outcomes. | The New England Journal of Medicine

Explore this annual collection of free articles that NEJM editors selected as the most meaningful in changing clinical practice and improving patient care in 2025. | The New England Journal of Medicine

NEJM Wrapped 2025 is here. Take a look back at the numbers that went into a year of publishing at the world’s leading medical journal. To discover the 15 articles NEJM editors selected as among the most impactful in advancing clinical practice and patient care this year, download the Notable Articles of 2025: https://nej.md/4peY19S | The New England Journal of Medicine

A new look. A familiar feel. The pulse of knowledge. For the pace of today. Announcing the newly redesigned NEJM website. | The New England Journal of Medicine

What is it like to be an NEJM editorial fellow for a year? This year’s fellows — Drs. Abarna Pearl, Sarah Gorey, Christos Kotanidis, and Harleen Marwah — discuss what they have learned, how their experience will help their career, and what surprised them. Applications for the 2026–27 NEJM editorial fellowship are now open. NEJM will accept applications for several one-year, full-time, paid editorial fellowships that begin July 2026. Deadline is Friday, August 1, 2025. To learn more and to apply,

The latest video in our partnership with Dr. Glaucomflecken summarizes the PENS trial, which investigated the effectiveness of shunt surgery for idiopathic normal-pressure hydrocephalus. Access the full trial results for free: https://nej.md/DrG34 | The New England Journal of Medicine